Drug

New Alzheimer's drug slows mental decline by 27% in clinical trial

New Alzheimer’s drug slows mental decline by 27% in clinical trial

Japanese pharmaceutical company Eisai and its partner, Cambridge-based Biogen, announced that their drug slowed cognitive decline in Alzheimer’s disease in a global trial. The drug, an antibody called lecanemab, slowed the rate of cognitive decline in volunteers by 27% compared to those given a placebo in the large late-stage trial. The companies plan to present …

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Senator Mike Lee wants to repeal the Inflation Reduction Act's drug price caps

Senator Mike Lee wants to repeal the Inflation Reduction Act’s drug price caps

Sen. Mike Lee is seeking to repeal provisions that cap prescription drug prices for Medicare and Medicaid patients. The Inflation Reduction Actwhich was signed into law in August, includes the requirement that the Centers for Medicare & Medicaid Services negotiate a maximum price for certain brand-name prescription drugs with no generic equivalent. The Republican Senator’s …

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Cambridge biotech wins approval for highly controversial ALS drug - The Boston Globe

Cambridge biotech wins approval for highly controversial ALS drug – The Boston Globe

Since 1995, only two drugs have been approved to treat amyotrophic lateral sclerosis — also known as Lou Gehrig’s disease — and neither works very well. “This approval provides another important treatment option for ALS, a rare and life-threatening disease that currently has no cure,” said Dr. Billy Dunn, director of the Office of Neuroscience …

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Experts offer stark assessment of Oregon's drug decriminalization policy so far

Experts offer stark assessment of Oregon’s drug decriminalization policy so far

Many people view Measure 110 as a contributor to the state’s drug addiction problem, and some argue that it should be repealed. SALEM, Ore. — It’s been almost two years since Oregon voters passed Measure 110, decriminalizing possession of small amounts of hard drugs. The plan was to use state marijuana tax money to create …

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USC researchers identify drug that could treat cancerous brain tumors

USC researchers identify drug that could treat cancerous brain tumors

LOS ANGELES — Identifying a small-molecule drug that can target circadian clock proteins in the brain could prove effective in treating glioblastoma, the most common cancerous brain tumor in adults, it was announced Monday researchers at USC’s Keck School of Medicine. Glioblastoma is an aggressive disease. Patients survive on average only 15 months once they …

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Illustration of nanoparticles with light shining through them

Molecular detection platform offers new insights into gene drug manufacturing

By Gina Wadas / Posted September 23, 2022 An important component of vaccines protecting people against the SARS-CoV-2 virus and its variants are lipid nanoparticles, or LNPs. These circular particles carry therapeutic mRNA payloads, the snippets of genetic material that trigger our immune system’s defense against COVID-19. Even with their success, some characteristics of the …

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Ionis Provides Update on Development Program Evaluating PCSK9 Antisense Drug for the Treatment of Hypercholesterolemia

Ionis Provides Update on Development Program Evaluating PCSK9 Antisense Drug for the Treatment of Hypercholesterolemia

ION449 (AZD8233) met the primary endpoint in phase 2b SOLANO study for patients with hypercholesterolemia ION449 will not proceed to Phase 3 development based on predefined criteria CARLSBAD, Calif., September 23, 2022 /PRNewswire/ — Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that key results from the 2b SOLANO A study in patients with hypercholesterolemia demonstrated …

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